언어 선택

Tau

Tau 분자 정보

영어 이름	Microtubule-associated protein tau	시판 약물 수	1
임상 약물 수	36	표적 별명	MAPT，MTBT1，Paired helical filament-tau，MAPTL，Microtubule Associated Protein Tau，G Protein Beta1/Gamma2 Subunit-Interacting Factor 1，Protein Phosphatase 1， Regulatory Subunit 103，Neurofibrillary Tangle Protein，PHF-Tau，TAU，Microtubule-Associated Protein Tau， Isoform 4，Microtubule-Associated Protein Tau，PPP1R103，FTDP-17，MTBT2，DDPAC，MSTD，PPND，tau Proteins，MGC138549，FLJ31424
최고 연구 개발 단계	Approved

영어 이름	Microtubule-associated protein tau
표적 별명	MAPT，MTBT1，Paired helical filament-tau，MAPTL，Microtubule Associated Protein Tau，G Protein Beta1/Gamma2 Subunit-Interacting Factor 1，Protein Phosphatase 1， Regulatory Subunit 103，Neurofibrillary Tangle Protein，PHF-Tau，TAU，Microtubule-Associated Protein Tau， Isoform 4，Microtubule-Associated Protein Tau，PPP1R103，FTDP-17，MTBT2，DDPAC，MSTD，PPND，tau Proteins，MGC138549，FLJ31424
시판 약물 수	1
임상 약물 수	36
최고 연구 개발 단계	Approved

Tau 제품 목록

속성
Protein (18)Cell (1)Antibody (2)
제품 라이브러리
온라인 (21)
종
Human (18)Cynomolgus (1)Mouse (2)
태그
His Tag (7)Tag Free (11)GFP Tag (1)- (1)Mouse IgG1 (1)
마커
Unconjugated (20)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT CHEK-ATP087	Human	HEK293	HEK293/Human Tau-K18 (GFP) Stable Cell Line
HOT TAU-H5113	Human	E. coli	Human Tau-441 K18 (P301L) Pre-formed Fibrils Protein, Tag Free
HOT TAU-H5115	Human	E. coli	Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free
HOT TAU-H5117	Human	E. coli	Human Tau-441 / 2N4R Protein, Tag Free, low endotoxin (MALS verified)
HOT TAU-H51H3	Human	E. coli	Human Tau-441 / 2N4R Protein, His Tag
TAU-H5112	Human	E. coli	Human Tau-381 / 1N3R Protein, Tag Free (MALS verified)
TAU-H5114	Human	E. coli	Human Tau Protein, Tag Free, low endotoxin (MALS verified)
TAU-H5116	Human	E. coli	Human Tau-441 K18 Pre-formed Fibrils Protein, Tag Free
TAU-H5118	Human	E. coli	Human Tau-441 (K18, P301L) Protein, Tag Free, low endotoxin (MALS verified)
TAU-H5119	Human	E. coli	Human Tau-412 / 1N4R Protein, Tag Free, low Endotoxin (MALS verified)

총 수량21

Tau분자 배경

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Tau분자 별명

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Buntanetap	ANVS-405; ANVS-401	Phase 3 Clinical	Raptor Pharmaceutical	Down Syndrome; Chronic Traumatic Encephalopathy; Alzheimer Disease; Parkinson Disease; Cognitive Dysfunction; Frontotemporal Dementia	상세
Florzolotau (Aprinoia Therapeutics)	[18F]PM-PBB3; APN-1607; 18F-PM-PBB3; 18F-APN-1607; [18F]APN-1607; [18F]MNI-958; APN-0000455; F0-PBB3; PM-PBB3	Phase 3 Clinical	Aprinoia Therapeutics Ltd	Supranuclear Palsy, Progressive; Nerve Degeneration; Alzheimer Disease; Cognitive Dysfunction; Diagnostic agents; Cognition Disorders	상세
E-2814	E-2814	Phase 3 Clinical	Eisai Co Ltd	Dementia; Alzheimer Disease	상세
Izaflortaucipir F-18	PI-2620; 18F-PI-2620; [18F]PI-2620	Phase 3 Clinical	Piramal, Ac Immune Sa	Supranuclear Palsy, Progressive; Brain Injuries, Traumatic; Opioid-Related Disorders; Frontotemporal Lobar Degeneration; Alzheimer Disease; Cognitive Dysfunction	상세
XTR-006	XTR-006	Phase 3 Clinical	Beijing Xiantong International Technology Co Ltd	Tauopathies; Alzheimer Disease	상세
Zagotenemab	LY-3303560	Phase 2 Clinical	Eli Lilly And Company	Alzheimer Disease	상세
Posdinemab	JNJ-3657; JNJ-63733657	Phase 2 Clinical	Johnson & Johnson Innovative Medicine	Dementia; Alzheimer Disease; Cognitive Dysfunction	상세
[18F]GTP-1	[18F]GTP-1	Phase 2 Clinical	Genentech Inc	Alzheimer Disease	상세
[18F]THK-5105	[18F]THK-5105	Phase 2 Clinical	Tohoku University	Alzheimer Disease	상세
ISIS-814907	BIIB-080; ISIS-814907; IONIS-MAPTRx; ISIS-BIIB4Rx; IONIS-BIIB4RX	Phase 2 Clinical	Biogen Inc, Ionis Pharmaceuticals Inc	Dementia; Cognitive Dysfunction; Alzheimer Disease	상세
Tilavonemab	C2N-8E12; ABBV-8E12	Phase 2 Clinical	C2n Diagnostics Llc	Supranuclear Palsy, Progressive; Alzheimer Disease	상세
Semorinemab	MTAU-9937A; MTAU9937A; RG-6100; RO7105705; RO-7105705	Phase 2 Clinical	Ac Immune Sa	Alzheimer Disease	상세
APN-1701	[18F]AM-PBB3; 18F-AM-PBB3; APN-1701	Phase 2 Clinical	National Institute Of Radiological Sciences, Aprinoia Therapeutics Ltd	Nerve Degeneration; Alzheimer Disease	상세
VY-TAU-01	VY-TAU01; VY-TAU-01; VY-7523	Phase 2 Clinical	Voyager Therapeutics Inc	Alzheimer Disease	상세
Anti-tau antibody (Prothena)	PRX-005; BMS-986446	Phase 2 Clinical	Prothena	Alzheimer Disease; Frontotemporal Dementia	상세
Bepranemab	UCB-0107; RG6416	Phase 2 Clinical	Ucb	Supranuclear Palsy, Progressive; Alzheimer Disease	상세
[18F]THK-5117	[18F]THK-5117	Phase 2 Clinical	Tohoku University	Alzheimer Disease	상세
PNT-001	PNT-001	Phase 1 Clinical	Beth Israel Deaconess Medical Center	Brain Injuries, Traumatic; Alzheimer Disease	상세
ReS19-T	ReS19-T	Phase 1 Clinical	Remynd	Alzheimer Disease	상세
Mecripyrine Hydrochloride	SCR-1693; Y-1A; Y-1	Phase 1 Clinical	Jiangsu Simcere Pharmaceutical Co Ltd, Yantai Yene Pharma Co Ltd, NeuroDawn Pharmaceutical Co Ltd	Brain Neoplasms; Alzheimer Disease	상세
Lu-AF87908	Lu-AF87908; Lu-AF-87908	Phase 1 Clinical	H. Lundbeck A/S	Alzheimer Disease	상세
RDC-5	RDC-5	Phase 1 Clinical	Chronos Therapeutics Ltd	Amyotrophic Lateral Sclerosis	상세
MC-1 (Lilly)	MC-1 (Lilly)	Phase 1 Clinical	Eli Lilly And Company	Alzheimer Disease	상세
OLX-07010	OLX07010	Phase 1 Clinical	Oligomerix Inc	Supranuclear Palsy, Progressive; Alzheimer Disease; Dementia; Neurodegenerative Diseases	상세
Protollin		Phase 1 Clinical		Alzheimer Disease	상세
AB-19 (AUTOTAC Bio)	AB-19 (AUTOTAC Bio)	Phase 1 Clinical	Autotac Bio Inc	Supranuclear Palsy, Progressive	상세
AB-12 po (AUTOTAC Bio)	AB-12 po	Phase 1 Clinical	Autotac Bio Inc	Alzheimer Disease	상세
[89Zr]Zr-DFO-BIIB080	[89Zr]Zr-DFO-ISIS-814907; [89Zr]Zr-DFO	Phase 1 Clinical	Biogen Inc		상세
DA-7503	DA-7503	Phase 1 Clinical	Dong-A ST Co Ltd		상세
LY-3954068	LY3954068; LY-3954068	Phase 1 Clinical	Eli Lilly And Company	Alzheimer Disease	상세
ADEL-Y01	ADEL-Y01	Phase 1 Clinical	Oscotec Inc, ADEL Inc	Tauopathies; Alzheimer Disease	상세
MK-2214	MK-2214	Phase 1 Clinical	Merck Sharp & Dohme LLC	Alzheimer Disease	상세
APNmAb-005	APNmAb-005	Phase 1 Clinical	Aprinoia Therapeutics Ltd	Nerve Degeneration; Alzheimer Disease; Tauopathies	상세
NIO-752	NIO-752	Phase 1 Clinical	Novartis Pharma Ag	Supranuclear Palsy, Progressive; Alzheimer Disease; Cognitive Dysfunction; Neurodegenerative Diseases	상세
BEY-2153	BEY-2153	Phase 1 Clinical	Beyondbio Inc	Alzheimer Disease	상세
11C-PBB3	11C-PBB3	Clinical	National Institute Of Radiological Sciences	Alzheimer Disease	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Flortaucipir F18	18F-AV-1451; [F18]AV1451; LY3191748; F-18-AV-1451; [18F]-T-807; [3H]AV 1451; T807; [F-18]T807	Approved	Siemens Medical Solution	Tauvid	United States	Alzheimer Disease	Avid Radiopharmaceuticals Inc	2020-05-28	Dementia; Frontotemporal Dementia; Neurodegenerative Diseases; Cognition Disorders; Corticobasal degeneration; Diagnostic agents; Cognitive Dysfunction; Tauopathies; Parkinson Disease; Supranuclear Palsy, Progressive; Alzheimer Disease; Pick Disease of the Brain; Aphasia, Primary Progressive; Chronic Traumatic Encephalopathy; Brain Concussion; Brain Injuries, Traumatic; Depression; Brain Injuries	상세

제품 리뷰

P***g2021-08-24
5사람들이 좋아합니다
Human Tau-441 / 2N4R Protein, His Tag
I have purchased multiple antigens from ACRO for discovery projects and I have found that the quality of antigens purchased from Acro is great!! Acro has become by go to vendor when I am looking for quality antigens. In addition, Acro also provides an impressive range of formats for each antigens, including different tags. Not to mention, their customer service team is fantastic. Overall, a great company to work with.