Human Tau-412 / 1N4R Protein, Tag Free, low Endotoxin (MALS verified)

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Cat. No. / Size
Price
Qty
TAU-H5119-100ug
₩441,000
TAU-H5119-1mg
₩3,087,000
ETA of in-stock products:2 business days

Product Details

  • Synonym

    DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU

  • Source

    Human Tau-412 Protein, Tag Free (TAU-H5119) is expressed from E. coli cells. It contains AA Met 1 - Leu 412 (Accession # P10636-7).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    Tau Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 43 kDa. The protein migrates as 43 kDa,45 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Tau SDS-PAGE

    Human Tau-412 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Tau SEC-MALS

    The purity of Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) is more than 90% and the molecular weight of this protein is around 35-55 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Tau ELISA

    Immobilized Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) at 1 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.06-8 ng/mL (QC tested).

    Protocol

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Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Recent Advances

 
Drug Development Progress
  • English Name:

    Microtubule-associated protein tau

  • Category:

  • Approved Drugs:

    1 Details

  • Drugs in Clinical Trials:

    46 Details

  • Highest Development Stage:

    Approved

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