Monoclonal Anti-RSV(B)-Pre-F0 specific Antibody, Human IgG1 (8E3) (MALS verified)

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제품 번호/규격
가격
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RSV-MY2246-100ug
₩525,000
RSV-MY2246-1mg (500ug X 2)
₩3,465,000
ETA of in-stock products:2 business days
총 항목 수 제품 금액0

제품 세부정보

  • Source

    Monoclonal Anti-RSV(B)-Pre-F0 specific Antibody, Human IgG1 (8E3) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    8E3

  • Species

    Mouse

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant HRSV (B) Pre-fusion glycoprotein F0 is expressed from human 293 cells

  • Specificity

    Specifically recognizes HRSV (B) Pre-fusion glycoprotein F0.

  • Application

    Application
    Recommended Usage
    ELISA
    0.06-250 ng/mL
  • Purity

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

    For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Cross Verification

    This product No cross-reactivity in ELISA with

    HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7).

    HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6).

    HRSV (B) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H9).

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    RSV(B)-Pre-F0 SDS-PAGE

    Monoclonal Anti-RSV(B)-Pre-F0 specific Antibody, Human IgG1 (8E3) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    RSV(B)-Pre-F0 SEC-MALS

    The purity of Monoclonal Anti-RSV(B)-Pre-F0 specific Antibody, Human IgG1 (8E3) (Cat. No. RSV-MY2246) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     RSV(B)-Pre-F0 ELISA

    Immobilized HRSV (B) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H8) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-RSV(B)-Pre-F0 specific Antibody, Human IgG1 (8E3) (Cat. No. RSV-MY2246) with a linear range of 0.06-16 ng/mL (QC tested).

    Protocol

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배경 소개

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation.

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