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CCR8

CCR8 Overview

English Name	C-C chemokine receptor type 8	Approved Drugs	0
Drugs in Clinical Trials	17	Target Synonym	Chemokine (C-C) Receptor 8，CC Chemokine Receptor 8，CDw198 Antigen，C-C CKR-8，CC-CKR-8，CCR-8，CMKBRL2，C-C Motif Chemokine Receptor 8，CC chemokine receptor CHEMR1，C-C chemokine receptor type 8，Chemokine (C-C Motif) Receptor 8，C-C Chemokine Receptor Type 8，CC Chemokine Receptor CHEMR1，Chemokine Receptor-Like 1，Chemokine (C-C) Receptor-Like 2，CC-Chemokine Receptor Chemr1，CD_antigen=CDw198，Chemokine receptor-like 1，CKRL1，CKR-L1，CMKBR8，GPRCY6，GPR-CY6，TER1，CDw198，CY6
Highest Development Stage	Phase 3 Clinical

English Name	C-C chemokine receptor type 8
Target Synonym	Chemokine (C-C) Receptor 8，CC Chemokine Receptor 8，CDw198 Antigen，C-C CKR-8，CC-CKR-8，CCR-8，CMKBRL2，C-C Motif Chemokine Receptor 8，CC chemokine receptor CHEMR1，C-C chemokine receptor type 8，Chemokine (C-C Motif) Receptor 8，C-C Chemokine Receptor Type 8，CC Chemokine Receptor CHEMR1，Chemokine Receptor-Like 1，Chemokine (C-C) Receptor-Like 2，CC-Chemokine Receptor Chemr1，CD_antigen=CDw198，Chemokine receptor-like 1，CKRL1，CKR-L1，CMKBR8，GPRCY6，GPR-CY6，TER1，CDw198，CY6
Approved Drugs	0
Drugs in Clinical Trials	17
Highest Development Stage	Phase 3 Clinical

CCR8 Product List

Product Category
Cell (1)Protein (8)Antibody (1)
Product Status
Launched (13)In Research (1)
Species
Human (7)Mouse (2)Rhesus macaque (1)
Tag
- (14)
Conjugate
- (5)Unconjugated (7)Biotin-labeled (2)

Cat. No.	Species	Host	Product Description
HOT CC8-H52D6	Human	HEK293	Human CCR8 Protein, Flag,His Tag&Twin-Strep Tag (Detergent)
HOT CC8-H52D7	Human	HEK293	Human CCR8 Protein, Flag,His Tag&Twin-Strep Tag (Nanodisc)
CC8-H52D4	Human	HEK293	Human CCR8 Full Length Protein, His,Flag Tag (Nanodisc-pro)
CC8-H52P5	Human	HEK293	Human CCR8 Protein (VLP)
CC8-H82D3	Human	HEK293	Biotinylated Human CCR8 Protein, His,Flag Tag&Avitag™ (Detergent)
CC8-H82D4	Human	HEK293	Biotinylated Human CCR8 Protein, His,Flag&Avitag™ (Nanodisc)
CHEK-ATP140	Human	HEK293	HEK293/Human CCR8 Stable Cell Line
CC8-M52P3	Mouse	HEK293	Mouse CCR8 Full Length Protein (VLP)
CC8-MY2406	Mouse	HEK293	Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (MALS verified)
CC8-R52P3	Rhesus macaque	HEK293	Rhesus macaque CCR8 Full Length Protein (VLP)

Total: 10

CCR8 Background

CCR8 is a G protein-coupled chemokine receptor expressed on regulatory T cells and in tumor microenvironments, mediating chemotaxis, immune regulation, and pathological processes like inflammation or cancer progression. The unconjugated anti-human CCR8 antibody enables specific detection of human CCR8.

CCR8 Synonyms

CC chemokine receptor 8,CDw198,ChemR1,CKRL1,CKR-L1,CKRL1,CY6,GPRCL1,GPRCY6,GPR-CY6,TER-1

Antibody Project Trading Platform

Project Name	Project Stage	Molecule Type	Molecule Source	Disease Area	Indication
CCR8 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Solid tumor
CCR8 mAb - 02	Lead	Monoclonal	Humanized Mouse	Solid Tumor	Solid tumor
CCR8 mAb - 03	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Solid tumor

Project Cooperation

Project Name	Drug Type	Therapeutic Area	Indication	Stage	Rights Area
CCR8 Humanized Antibody	Bispecific antibody	Oncology/Cancer	Solid Tumor	Preclinical	Global

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
BMS-986340	BMS-986340; ONO-7427	Phase 2 Clinical	Eeig Bristol-Myers Squibb Manufacturing Company Bristol-Myers Squibb Srl	Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms	Details
DT-7012	DT-7012	Phase 2 Clinical	Domain Therapeutics SA	Solid tumours; Neoplasms	Details
S-531011	S-531011	Phase 2 Clinical	Shionogi Inc	Solid tumours	Details
LM-108	LM-108	Phase 2 Clinical	LaNova Medicines Ltd	Solid tumours; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
anti-CCR8 antibody (Bristol-Myers Squibb)		Phase 1 Clinical	Bristol-Myers Squibb Company	Solid tumours	Details
BAY-3375968	BAY-3375968	Phase 1 Clinical	Bayer AG	Solid tumours; Neoplasms	Details
ICP-B05	CM-369; ICPB05	Phase 1 Clinical	Keymed Biosciences Co Ltd, InnoCare Pharma Ltd	Solid tumours; Hematologic Neoplasms	Details
HBM-1022	HBM-1022	Phase 1 Clinical	Harbour Biomed	Neoplasms	Details
JTX-1811	JTX-1811; GS-1811	Phase 1 Clinical	Jounce Therapeutics Inc	Solid tumours	Details
CHS-114	SRF-114; CHS-114	Phase 1 Clinical	Surface Oncology Inc	Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms	Details
AMG-355	AMG 355; AMG-355	Phase 1 Clinical	Amgen Inc	Solid tumours	Details
HC-006	HC-006; HC006	Phase 1 Clinical	Shanghai Hongcheng Pharmaceutical Co Ltd	Solid tumours	Details
BGB-A3055	BGB-A3055	Phase 1 Clinical	BeOne Medicines Ltd	Solid tumours	Details
QLP2117	QLP2117; QLP-2117	Phase 1 Clinical	Qilu Pharmaceutical Co Ltd	Solid tumours	Details
ABBV-514	ABBV-514	Phase 1 Clinical	Abbvie Inc	Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung	Details
IPG-7236	IPG-7236	Phase 1 Clinical	Nanjing Immunophage Biotech Co Ltd	Solid tumours; Breast Neoplasms; Dermatitis, Atopic	Details
ZL-1218	ZL-1218	Phase 1 Clinical	Zai Lab (Shanghai) Co Ltd	Solid tumours; Neoplasms	Details